Search results for "Systemic circulation"

showing 3 items of 3 documents

Absorption of Drugs after Oral Administration

2007

After oral administration, drugs must be absorbed through the gastrointestinal tract to achieve the systemic circulation and exert their pharmacological effects. The successful formulation of an optimized oral drug delivery system requires a detailed consideration and a good understanding of the intestinal absorption process, its possibilities and limitations. This article gives an overview and update on the concepts, possibilities, and limitations of drug absorption after oral administration. Keywords: oral administration; drug absorption; oral drug delivery system; gastrointestinal tract; intestinal absorption

Absorption (pharmacology)stomatognathic diseasesGastrointestinal tractbusiness.industryOral administrationMedicineDelivery systemPharmacologybusinessEnteral administrationSystemic circulationIntestinal absorptionOral retinoid
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Zur Wirkung von Muskelrelaxantien auf den intraokularen Druck

1988

Since general anesthesia is being used increasingly in ophthalmic surgery, the effects of anesthetic drugs on intraocular pressure (IOP) have to be considered. Competitive neuromuscular blocking drugs either do not affect IOP or produce a slight decrease. Depolarizing muscle relaxants increase IOP. This effect, which is pronounced with succinylcholine, cannot be reliably prevented by any concomitant medication. The new competitive relaxants atracurium and vecuronium provide stable conditions with respect to IOP and systemic circulation, combined with fast onset and intermediate duration of action.

Intraocular pressuregenetic structuresbusiness.industryDepolarizing muscle relaxantsFast onsetSystemic circulationeye diseasesOphthalmologyAnesthesiaAnestheticMedicinesense organsbusinessOphthalmic surgerymedicine.drugKlinische Monatsblätter für Augenheilkunde
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Multiple pulmonary and multivesicular interatrial septum hydatid cysts in a native italian patient

2008

Multivesicular, pulmonary and cardiac hydatidosis are rarely observed and can give rise to serious complications. Cysts can remain asymptomatic for a long time, until they reveal themselves perforating into cardiac chambers and/or pulmonary arteries or the systemic circulation. A rare case of multivesicular interatrial septum hydatid cyst with multiple pulmonary involvement in a native Italian farm labourer is reported. Clinical, radiological, serological and histological findings are described. MR imaging showed the exact anatomic location and the multivesicular nature of the cardiac cyst and was useful in planning surgical treatment. A successful outcome was achieved with a combination of…

medicine.medical_specialtyChemotherapybiologySettore MED/17 - Malattie Infettivebusiness.industrymedicine.medical_treatmentbiology.organism_classificationmedicine.diseaseSystemic circulationAsymptomaticSurgeryAlbendazoleInfectious Diseasesmedicine.anatomical_structuremedicineCystEchinococcus granulosus cardiac hydatidosis multivesicular hydatic cyst pulmonary hydatidosismedicine.symptomEchinococcus granulosusbusinessmedicine.drugInteratrial septumRare disease
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